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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX6
All Species:
14.85
Human Site:
Y427
Identified Species:
27.22
UniProt:
O95947
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95947
NP_004599.2
436
47045
Y427
P
Y
T
A
P
G
G
Y
L
D
V
G
S
K
P
Chimpanzee
Pan troglodytes
XP_523337
436
47083
Y427
P
Y
T
A
P
G
G
Y
L
D
V
G
S
K
P
Rhesus Macaque
Macaca mulatta
XP_001098963
496
53657
S481
P
H
N
A
Q
P
P
S
E
E
E
G
R
V
T
Dog
Lupus familis
XP_547068
436
47185
Y427
A
Y
P
G
P
G
A
Y
L
D
V
G
S
K
P
Cat
Felis silvestris
Mouse
Mus musculus
P70327
540
58610
S520
H
L
S
A
N
G
G
S
L
C
L
A
K
W
G
Rat
Rattus norvegicus
Q5I2P1
517
57726
V504
S
P
H
Q
Y
H
S
V
H
G
V
G
M
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520749
277
31432
P269
R
R
L
R
G
P
E
P
A
L
T
D
T
Y
A
Chicken
Gallus gallus
P79779
361
41167
P353
E
H
D
S
K
Q
L
P
E
G
F
T
N
L
P
Frog
Xenopus laevis
Q8AV66
506
56540
S462
P
S
C
A
V
T
P
S
V
R
L
S
D
E
P
Zebra Danio
Brachydanio rerio
P79742
473
53459
T456
E
Y
T
D
Q
Q
F
T
L
N
S
Q
T
E
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
P708
P
N
I
S
V
G
P
P
I
H
P
S
P
H
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
F414
T
P
P
K
K
G
G
F
D
V
L
D
L
L
S
Sea Urchin
Strong. purpuratus
XP_797010
645
70075
M533
S
Y
C
S
G
Q
G
M
G
L
Q
G
S
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
81.8
90.1
N.A.
64.4
34.8
N.A.
43.8
35
43
37
N.A.
22.8
N.A.
35.5
30.2
Protein Similarity:
100
99
83.2
92.1
N.A.
67.9
48.5
N.A.
48.3
47.4
54.5
52.8
N.A.
30.7
N.A.
52.5
43.8
P-Site Identity:
100
100
20
73.3
N.A.
26.6
20
N.A.
0
6.6
20
20
N.A.
13.3
N.A.
13.3
26.6
P-Site Similarity:
100
100
33.3
73.3
N.A.
40
20
N.A.
6.6
26.6
40
40
N.A.
26.6
N.A.
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
39
0
0
8
0
8
0
0
8
0
0
8
% A
% Cys:
0
0
16
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
0
8
24
0
16
8
0
0
% D
% Glu:
16
0
0
0
0
0
8
0
16
8
8
0
0
16
0
% E
% Phe:
0
0
0
0
0
0
8
8
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
8
16
47
39
0
8
16
0
47
0
0
16
% G
% His:
8
16
8
0
0
8
0
0
8
8
0
0
0
8
8
% H
% Ile:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
16
0
0
0
0
0
0
0
8
24
0
% K
% Leu:
0
8
8
0
0
0
8
0
39
16
24
0
8
16
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
0
8
8
0
8
0
0
0
0
8
0
0
8
0
0
% N
% Pro:
39
16
16
0
24
16
24
24
0
0
8
0
8
0
47
% P
% Gln:
0
0
0
8
16
24
0
0
0
0
8
8
0
0
0
% Q
% Arg:
8
8
0
8
0
0
0
0
0
8
0
0
8
0
0
% R
% Ser:
16
8
8
24
0
0
8
24
0
0
8
16
31
8
8
% S
% Thr:
8
0
24
0
0
8
0
8
0
0
8
8
16
0
8
% T
% Val:
0
0
0
0
16
0
0
8
8
8
31
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
39
0
0
8
0
0
24
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _